When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement…read on In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible. Together we define white space, push boundaries and empower people to solve problems. If you’re someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we’ll ask “why not?” and help reengineer the future of biopharma. What You’ll Do We are looking for a Director of Infrastructure & Cloud Services to lead the global cloud strategy for the IT Infrastructure team and report directly to the Senior Director of IT. This role will plan, architect, develop, organize, and work with teams to implement the next generation of server, storage, and cloud solutions to support the expansive growth of data and systems within BridgeBio. To ensure system reliability and uptime, the individual will provide thoughtful leadership around capacity planning, backup and recovery, high availability, business continuity, disaster recovery, and infrastructure operations. The primary success of this position will be measured by how effectively IT rolls out a cloud-first server and storage infrastructure environment, enabling rapid access to compute resources and cloud services (whether in the office or remote), and how security and quality measures are applied to secure our assets while minimizing intrusiveness to the staff. Responsibilities Strategic Leadership & Business Alignment Partner with business leaders to understand their needs and ensure infrastructure investments are prioritized, scoped, delivered, and managed in alignment with business requirements Develop and maintain the IT infrastructure operations strategy and roadmap (Server, Storage, Cloud), evolving the 3-year IT roadmap and system inventory in alignment with the budget process Prepare and present project proposals, system configurations, and deployment cost estimates to management and business partners Conduct ongoing research into industry and technology trends, evaluate key developments, and recommend solutions to drive business value and efficiencies Technology Innovation & Delivery Recommend innovative technology solutions based on industry best practices (e.g., cloud migration strategies, modernization roadmaps) Lead the successful delivery of infrastructure solutions within the IT portfolio, including servers, systems software, cloud infrastructure, cloud backup services, and related security Identify and engage partner vendors, leading the rollout of services to support BridgeBio’s server, storage, and cloud infrastructure Facilitate the evaluation and recommendation of new technologies or capabilities applicable across the business Operations, Security & Compliance Build and manage operations and support functions for infrastructure monitoring, management, and cloud services security Ensure infrastructure availability, resilience, and disaster recovery are maintained to support mission-critical operations Partner with Validation/QA and Compliance teams to ensure infrastructure meets regulatory requirements (e.g., SOX, HIPAA, GDPR, or applicable industry standards) Oversee security standards, patching, and vulnerability management for all servers, storage, and cloud platforms Lead managed service providers in monitoring and supporting core infrastructure services Prepare and manage infrastructure-related cost estimates, budgets, and schedules. Monitor and control the annual department budget to ensure expenditures align with the business plan Optimize vendor contracts, licensing, hardware, and cloud usage to control costs and improve ROI Select, develop, and evaluate personnel to ensure efficient operation of the infrastructure function Mentor and lead a high-performing team, fostering a culture of accountability, innovation, and continuous improvement Collaborate with cross-functional IT and business teams to deliver integrated solutions that advance organizational goals Where You’ll Work This is a hybrid role and requires in-office collaboration 2- 3x per week in our San Francisco Office. Who You Are Bachelor’s degree in Computer Science, Information Technology, Business Administration, or a related field; Master’s degree preferred 10+ years of progressive IT experience, with at least 5 years in a leadership role overseeing infrastructure teams and enterprise systems Deep expertise in IT Infrastructure management, with a strong track record in the Life Sciences industry, including FDA-regulated environments with SOX and GxP compliance Proven ability to design, implement, and manage hybrid IT environments that integrate SaaS solutions, cloud platforms (Microsoft Azure, AWS), and on-premises infrastructure Hands-on experience with Windows and Linux operating systems, enterprise productivity and security platforms (Microsoft 365, Okta), and cloud security best practices Proficiency in automation and scripting (e.g., PowerShell), with knowledge of AI applications in IT operations preferred Demonstrated success applying SDLC methodologies to deliver complex IT projects, ensuring compliance, scalability, and efficiency Strong leadership and stakeholder management skills, with the ability to partner with business units, influence decision-making, and build consensus across cross-functional teams Exceptional organizational and project management skills; proven ability to lead through change, drive continuous improvement, and align infrastructure strategy with business objectives Excellent verbal and written communication skills, with the ability to present technical concepts to technical and non-technical audiences Ability to operate in a cross-functional / matrix environment Rewarding Those Who Make the Mission Possible We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return. Market leading compensation 401K with 100% employer match on first 3% & 50% on the next 2% Employee stock purchase program Referral program with $2,500 award for hired referrals Comprehensive health care with 100% premiums covered – no cost to you and dependents Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions) Hybrid work model – employees have the autonomy in where and how they do their work Unlimited flexible paid time off – take the time that you need Paid parental leave – 4 months for birthing parents & 2 months for non-birthing parents Flex spending accounts & company-provided group term life & disability Subsidized lunch via Forkable on days worked from our office Skill Development & Career Paths: People are part of our growth and success story – from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits.

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