Join to apply for the Head of Software Engineering role at DELFI Diagnostics Join to apply for the Head of Software Engineering role at DELFI Diagnostics This range is provided by DELFI Diagnostics. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more. Base pay range $270,000.00/yr - $310,000.00/yr Direct message the job poster from DELFI Diagnostics Join me at DELFI to save lives through early cancer detection About Us DELFI Diagnostics, Inc. (DELFI Diagnostics) is developing next-generation, blood-based tests that are reliable, accessible and deliver a new way to help detect cancer. Employing advanced machine-learning methods to whole-genome sequencing data, the DELFI ("DNA EvaLuation of Fragments for early Interception") platform is built to address the highest-burden health challenges. DELFI Diagnostics prioritizes solutions that have the potential to save lives on a global scale, including for historically underserved populations. DELFI Diagnostics’ platform relies on fragmentomics – the discovery that cancer cells are more chaotic than normal cells and, when they die, leave behind tell-tale patterns and characteristics of cell-free DNA (cfDNA) fragments. FirstLook Lung, for individuals eligible for lung cancer screening, is DELFI Diagnostics’ first laboratory-developed screening test and can be part of routine blood work. FirstLook Lung uses millions of data points to reliably identify individuals who may have cancer detected through low-dose CT, including early stage disease with a negative predictive value of 99.8 percent. This test has not been cleared or approved by the FDA. In our passionate pursuit to radically improve health outcomes, we serve humanity when we: Lead with Science, Anchor in Pragmatism : We pioneer life-changing science by ensuring quality, transparency, and rigor at all times. We explore thoughtfully, experiment smartly, and deliver impact with conviction. Build With & For All : We embrace diverse backgrounds to innovate and achieve together. We are not just building a product - we aim to disrupt the path of cancer for all - no matter geography or socioeconomic class Put We over I : We are a home for high-performing people. Through teamwork, we build collective intelligence. Each of us wins when those we serve and those who serve with us--win. We show up with empathy, humility, and integrity at every step of the journey. DELFI has 1-2 designated in-office working days each week for employees who live within within 50 miles of Palo Alto CA or Baltimore MD offices The head of Software Engineering is a seasoned software leader who works at the interface of lab- & commercial-facing software and bioinformatics/ML production pipelines, and manages a team of software engineers, bioinformatics engineers, software/data architect, and software PMs. This role will collaborate closely with teams in information security & devops, software quality & test, data science/machine learning, and clinical development to ensure that DELFI’s software is performant and scalable. Reporting to the CTO, you will work closely with commercial and laboratory leadership, and with the PMO. This position requires expertise in software development and architecture, regulatory-grade lab-facing software in biotech and diagnostics, team leadership, and strong communication skills. This role is an excellent fit for those who are decisive, proactive and bring a balance of high IQ and EQ. About Us DELFI Diagnostics, Inc. (DELFI Diagnostics) is developing next-generation, blood-based tests that are reliable, accessible and deliver a new way to help detect cancer. Employing advanced machine-learning methods to whole-genome sequencing data, the DELFI ("DNA EvaLuation of Fragments for early Interception") platform is built to address the highest-burden health challenges. DELFI Diagnostics prioritizes solutions that have the potential to save lives on a global scale, including for historically underserved populations. DELFI Diagnostics’ platform relies on fragmentomics – the discovery that cancer cells are more chaotic than normal cells and, when they die, leave behind tell-tale patterns and characteristics of cell-free DNA (cfDNA) fragments. FirstLook Lung, for individuals eligible for lung cancer screening, is DELFI Diagnostics’ first laboratory-developed screening test and can be part of routine blood work. FirstLook Lung uses millions of data points to reliably identify individuals who may have cancer detected through low-dose CT, including early stage disease with a negative predictive value of 99.8 percent. This test has not been cleared or approved by the FDA. In our passionate pursuit to radically improve health outcomes, we serve humanity when we: Lead with Science, Anchor in Pragmatism : We pioneer life-changing science by ensuring quality, transparency, and rigor at all times. We explore thoughtfully, experiment smartly, and deliver impact with conviction. Build With & For All : We embrace diverse backgrounds to innovate and achieve together. We are not just building a product - we aim to disrupt the path of cancer for all - no matter geography or socioeconomic class Put We over I : We are a home for high-performing people. Through teamwork, we build collective intelligence. Each of us wins when those we serve and those who serve with us--win. We show up with empathy, humility, and integrity at every step of the journey. DELFI has 1-2 designated in-office working days each week for employees who live within within 50 miles of Palo Alto CA or Baltimore MD offices The head of Software Engineering is a seasoned software leader who works at the interface of lab- & commercial-facing software and bioinformatics/ML production pipelines, and manages a team of software engineers, bioinformatics engineers, software/data architect, and software PMs. This role will collaborate closely with teams in information security & devops, software quality & test, data science/machine learning, and clinical development to ensure that DELFI’s software is performant and scalable. Reporting to the CTO, you will work closely with commercial and laboratory leadership, and with the PMO. This position requires expertise in software development and architecture, regulatory-grade lab-facing software in biotech and diagnostics, team leadership, and strong communication skills. This role is an excellent fit for those who are decisive, proactive and bring a balance of high IQ and EQ. What You'll Do Manage and lead a team of software and bioinformatics engineers, software & data architect, and software product managers Oversee the productization and delivery of cutting-edge machine learning algorithms to detect cancer from blood samples Partner as needed with regulatory and software QA/testing/cybersecurity teams to maintain software as a medical device underlying diagnostic product(s) on market Collaborate with peers leading assay design & development, laboratory operations, data science, and clinical development to substantively advance DELFIs R&D objectives Develop and continuously improve software solutions for EHR integration and LIMS to enable machine learning as well as commercial sales Partner with IT & cybersecurity team lead to develop a 2-3 year technology roadmap, including in-house tooling for GenAI and ML infrastructure Represent DELFI externally with collaborators and vendors

What You'll Bring to DELFI Required Degree in any of the quantitative sciences (Applied Math, Physics, Chemistry, Computer Science) or Engineering 10+ years of software leadership experience in industry including track record of successfully developing and deploying lab and enterprise software, scalable data systems, and/or production ML infrastructure 15+ years expertise in programming including production compute environments (AWS/Nvidia), data systems (Postgres, RDS), and versioning principles for reproducible model-building and evaluation 10+ years of experience leading and managing teams exemplifying best practice in recruiting, team-building, employee performance management and career development, goal-setting, and cross-functional collaboration Superb written, verbal communication, and influencing and presentation skills, including the ability to communicate complex concepts succinctly to a variety of audiences Decisive, intellectually curious, proactive, and composed with a balance of high IQ and EQ Preferred 5+ years of experience working in biotech/pharma/diagnostics Background or interest in cancer genomics, molecular biology, and the latest genotyping and phenotyping techniques

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. This position is not eligible for agency partnership. Resumes and outreach from staffing representatives will be declined.

Total Compensation at DELFI is a combination of salary, bonus, equity, and benefits. Actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skillset, years & depth of experience, certifications & relevant education, geography. Seniority level Seniority level Not Applicable Employment type Employment type Full-time Job function Job function Engineering and Information Technology Industries Biotechnology Research, Technology, Information and Internet, and Software Development Referrals increase your chances of interviewing at DELFI Diagnostics by 2x Sign in to set job alerts for “Head of Software Engineering” roles. Sunnyvale, CA $208,000.00-$416,000.00 1 week ago Menlo Park, CA $250,000.00-$300,000.00 3 weeks ago Software Engineering Manager, Systems and Infrastructure Sunnyvale, CA $169,000.00-$338,000.00 1 week ago San Jose, CA $179,300.00-$354,600.00 1 week ago San Jose, CA $255,000.00-$300,000.00 1 week ago Manager, Software Engineering, Observability Mountain View, CA $147,000.00-$240,000.00 2 weeks ago Mountain View, CA $231,000.00-$312,000.00 1 week ago Manager, Software Engineering - Agents Platform San Mateo, CA $201,400.00-$302,000.00 1 week ago Pleasanton, CA $216,700.00-$433,300.00 1 week ago Mountain View, CA $231,000.00-$312,000.00 1 week ago Manager, Software Engineering, Media Platform San Jose, CA $188,000.00-$323,950.00 8 hours ago Menlo Park, CA $259,100.00-$388,700.00 4 weeks ago Software Engineering Manager, Infrastructure San Jose, CA $233,200.00-$311,300.00 2 weeks ago VP, Software Engineering, Industries SPARK Sr. Director of Engineering - Developer Experience Sunnyvale, CA $264,000.00-$342,000.00 1 week ago Mountain View, CA $165,900.00-$298,800.00 1 week ago Sunnyvale, CA $197,000.00-$291,000.00 2 weeks ago VP, Engineering - AI Software, HPE Private Cloud San Jose, CA $192,500.00-$443,500.00 1 day ago Sunnyvale, CA $261,000.00-$313,000.00 2 days ago Software Engineering Manager II, Google Cloud Compute Sunnyvale, CA $197,000.00-$291,000.00 6 days ago Software Engineering Manager, Infrastructure Sunnyvale, CA $177,000.00-$251,000.00 5 days ago Director, ADAS Perception Software Engineering and Machine Learning Software Engineering Manager, Infrastructure Software Engineering Manager - Backend Services Foster City, CA $241,000.00-$289,000.00 2 weeks ago Software Engineering Manager II, Infrastructure, Google Cloud Sunnyvale, CA $197,000.00-$291,000.00 1 week ago We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.

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